LH- and FSH-releasing activities of synthetic tetrapeptide and synthetic LH-RH in rats.
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منابع مشابه
3 H-labelling of a synthetic decapeptide having LH and FSH releasing activity (LH-RH--FSH-RH).
A decapeptide capable to stimulate the release of LH and FSH from pituitary has been recently isolated from hypothalami of porcine origin and its amino acid sequence has been established as (Pyro)Glu-HisTrp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH, [ 1,2]. An identical decapeptide has been found in sheep hypothalami [ 3,4] . Several laboratories described syntheses of LH-RH/FSH-RH either by the solid pha...
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Synthetic luteinizing hormone/follicle stimulating hormone-releasing hormone (LH/FSH-RH) (50 mug) was given intravenously to six women with oligomenorrhoea and to four women with secondary amenorrhoea. Peripheral venous blood was withdrawn at regular intervals over a 24-hour period. The concentrations of LH, FSH, and oestradiol-17beta were determined by radioimmunoassay. In all subjects there w...
متن کاملQuick release of FSH stimulated by repeated applications of synthetic luteinizing hormone-releasing hormone (LH-RH) in immature male rats.
Serum FSH and LH levels were estimated by radioimmunoassay following single subcutaneous administration, and repeated subcutaneous administration at various intervals in immature male rats. Single injection of LH-RH induced slight increase in FSH levels in comparison with considerable increase in LH. By two successive injections, the release of FSH was markedly stimulated when the time interval...
متن کاملResponse of serum LH, FSH and prolactin to injection of synthetic LH-RH into rat anterior pituitary.
Changes in serum LH, FSH and prolactin were measured by radioimmunoassay following injection of synthetic LH-RH into the anterior pituitary and median eminence of rats. The time course of serum levels of LH and FSH after injection of synthetic LH-RH into the pituitary showed a peak at 15 min. The synthetic LH-RH had a more marked releasing effect on LH than on FSH. After injection of 20 ng into...
متن کاملPlasma LH concentrations after single or double injections of synthetic LH-RH in dairy cows.
Milked Friesian dairy cows were given 1 or 2 i.v. injections of synthetic LH-RH. The second of 2 injections of LH-RH given 1.5 h apart induced a significantly greater release of LH than did the first. The response to this injection was also significantly greater than that caused by injections given 6 h apart. There was no significant difference between the LH responses to the two injections giv...
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ژورنال
عنوان ژورنال: The Tohoku Journal of Experimental Medicine
سال: 1976
ISSN: 0040-8727,1349-3329
DOI: 10.1620/tjem.119.393